In more than 90 percent of cases, the first to go bad is one called APC . APC is known as a cancer suppressor gene, since its usual duty is overseeing other genes that regulate the normal cycle of cells'growth and death.
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The result does not necessarily mean that the gene is not connected with colon cancer, said Dr . Eric R . Fearon of the University of Michigan, who originally identified DCC ( for " deleted in colorectal cancer " ) as a possible colon cancer suppressor gene, because the experiment was done in mice and they are not always a good model for human cancer development.
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